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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZFP36 All Species: 16.97
Human Site: S228 Identified Species: 53.33
UniProt: P26651 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P26651 NP_003398.1 326 34003 S228 P P G D L P L S P S A F S A A
Chimpanzee Pan troglodytes XP_001136016 503 53607 S405 P P G D L P L S P S A F S A A
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_541624 277 29561 A192 A R A S A S R A C P P A A D R
Cat Felis silvestris
Mouse Mus musculus P22893 319 33595 S220 P P G D L P L S P S A F S A A
Rat Rattus norvegicus P47973 320 33635 S221 P P G D L P L S P S A F S A A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521042 345 36095 S252 C S S S S S S S S S S S S S S
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002665468 361 39655 G267 V S P P P S T G S P D L L S P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P47980 436 47147 S260 G G G G G G N S I N N N N G S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 64.6 N.A. 64.7 N.A. 84.3 85.2 N.A. 34.2 N.A. N.A. 39 N.A. 29.1 N.A. N.A. N.A.
Protein Similarity: 100 64.6 N.A. 70.5 N.A. 88.9 90.1 N.A. 44 N.A. N.A. 48.7 N.A. 37.3 N.A. N.A. N.A.
P-Site Identity: 100 100 N.A. 0 N.A. 100 100 N.A. 20 N.A. N.A. 0 N.A. 13.3 N.A. N.A. N.A.
P-Site Similarity: 100 100 N.A. 13.3 N.A. 100 100 N.A. 40 N.A. N.A. 6.6 N.A. 33.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 13 0 13 0 13 0 0 13 0 0 50 13 13 50 50 % A
% Cys: 13 0 0 0 0 0 0 0 13 0 0 0 0 0 0 % C
% Asp: 0 0 0 50 0 0 0 0 0 0 13 0 0 13 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 50 0 0 0 % F
% Gly: 13 13 63 13 13 13 0 13 0 0 0 0 0 13 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 13 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 50 0 50 0 0 0 0 13 13 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 13 0 0 13 13 13 13 0 0 % N
% Pro: 50 50 13 13 13 50 0 0 50 25 13 0 0 0 13 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 13 0 0 0 0 13 0 0 0 0 0 0 0 13 % R
% Ser: 0 25 13 25 13 38 13 75 25 63 13 13 63 25 25 % S
% Thr: 0 0 0 0 0 0 13 0 0 0 0 0 0 0 0 % T
% Val: 13 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _